A puromycin-dependent activity-based sensing probe for histochemical staining of hydrogen peroxide in cells and animal tissues

Kaede Hoshi, Marco S. Messina, Jun Ohata, Clive Yik-Sham Chung, Christopher J. Chang

Published: 2022-05-12 DOI: 10.1038/s41596-022-00694-7

Hydrogen Peroxide

Activity-Based Probe

Peroxymycin-1

Chemoselective Oxidation

Histochemical Staining

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Hydrogen peroxide (H2O2) is a key member of the reactive oxygen species family of transient small molecules that has broad contributions to oxidative stress and redox signaling. The development of selective and sensitive chemical probes can enable the stu
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ACKNOWLEDGMENTS

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A puromycin-dependent activity-based sensing probe for histochemical staining of hydrogen peroxide in cells and animal tissues

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